
Samantha C. Mannese, FNP
HematologyMedical Oncology
Highlights
Age Groups Seen
- Adult 18-65
- Older Adult >65
Languages
- English
Gender
FemaleHospital Affiliations
- Nuvance Health - Northern Dutchess Hospital
- Nuvance Health - Vassar Brothers Medical Center
About Samantha C. Mannese
Professional Statement
Samantha Mannese is a board-certified Nurse Practitioner. She received her nursing education, both bachelor's and master's degrees, from Mount Saint Mary College in Newburgh, NY. As a registered nurse, she spent most of her career working on an inpatient oncology unit, which sparked her passion for working with the hematology/oncology patient population long term. After graduating with her nurse practitioner degree in 2018, she accepted a position working in the outpatient hematology/oncology setting. She travels to both the Poughkeepsie (Dyson Center) and Rhinebeck locations weekly to see patients in both offices. Her job is her passion, and she loves coming to work every day. She looks forward to getting to know patients and providing them with heartfelt, quality care.
Get To Know Me
Why should someone choose you to care for their health?
I believe that a patient should choose me to care for their health because I truly care about their overall wellbeing; both physically and emotionally. I want to spend the time to get to know my patients on a personal level, hear their stories, and understand what is most important to them when it comes to their care and treatment.
What is the most important thing your patients should expect from their professional relationship with you? What do you expect from them?
My patients should expect that I will give them my best at every visit. I will practice active listening, I will give them space to talk about their issues, and I will provide a safe environment to discuss concerns and needs. I want my patients to know that I will always be available to them even after or in-between visits and that their wellbeing is my top priority. In return, I expect my patients and their family members to be open and honest with me so that we can have a mutually respectful relationship.
How do you spend your valuable personal time when you are not caring for patients?
When I am not at work caring for my patients, I am spending time at home with my husband and three beautiful children along with our two dogs. We enjoy spending quiet weekends outdoors together or with our larger extended family. I also enjoy reading fiction novels, doing jigsaw puzzles, and attempting crossword puzzles!
Why did you choose your specialty and what is its greatest reward?
I chose to specialize in oncology because of how rewarding this field is. The patients we treat are true superheroes, and I have learned so much strength and resilience from them. I love to see how a community can come together to care for an individual and family struggling through a difficult diagnosis.
Expertise
Education
- Graduate: Mount St. Mary College, 2018
Board Certifications
- Family Nurse Practitioner: American Nurses Credentialing Center (ANCC)
Locations
- Nuvance Health Medical Practice - Medical Oncology Rhinebeck
- 6511 Spring Brook Avenue, Suite 101, Rhinebeck, NY 12572
- Get Directions
- phone: 845-871-3545
- fax: 845-871-3546
- Nuvance Health Medical Practice - Medical Oncology Poughkeepsie
- 45 Reade Place, Dyson Center For Cancer Care, Poughkeepsie, NY 12601
- Get Directions
- phone: 845-483-6001
- fax: 845-483-6002
Insurance
- Aetna
- Capital District Physicians' Health Plan
- Centivo
- Cigna
- Coventry-Aetna
- Emblem Health
- EmblemHealth
- Empire BlueCross Blue Shield
- Empire Health Plan
- Empire Plan
- Fidelis Care
- Hamaspik
- MagnaCare
- Medicaid Connecticut
- Medicaid New York
- Medicare New York
- Medicare Railroad
- Multiplan Inc
- MVP Health Care
- Northwell Direct
- Oxford Health Plans
- Tricare Humana Military
- United Healthcare
- Wellcare
Ratings & Reviews
5 out of 5
143 ratings, 11 reviewsProvider star ratings are calculated using patient responses to the provider care questions in our patient experience survey. Below you can see the provider’s star rating and the number of his or her patients who have provided feedback. Ratings depicted represent those clinicians that have at least 30 completed surveys on a rolling 12 month basis.
- 5 out of 5 starsReviewed on 12/16/2025
Samantha is consistently a bright and positive provider who goes above and beyond. She is patient with questions, informative, clearly explains things, open to needs of the patient. She is also highly responsive and quick in her communications in person a need through the portal.
- 5 out of 5 starsReviewed on 12/15/2025
Samantha is absolutely the best Medical Care professional I have had the good fortune to be under the care of. It is important, for me to tell you, that it is a privilege, for both of us, to be able to work with her. TY for this opportunity to let it be know
- 5 out of 5 starsReviewed on 12/12/2025
Absolutely love her she listens to you, and she gives you her opinion and is very easy to understand in layman terms
- 5 out of 5 starsReviewed on 7/25/2025
Samantha goes above and beyond for me , her care is the reason I’m alive
- 5 out of 5 starsReviewed on 7/23/2025
She was excellent and informative. She answered all my questions.
- 5 out of 5 starsReviewed on 7/5/2025
She is AMAZING!!! IM VERY GRATEFUL , SAMANTHA AND CARISSA THEY BOTH ARE UNBELIEVABLE KIND I APPRECIATE THEM SO MUCH. THANK YOU.
- 5 out of 5 starsReviewed on 6/30/2025
She was very personable and easy to talk to. She was attentive and reassuring. I would definitely recommend her care and professionalism to others.
- 5 out of 5 starsReviewed on 6/12/2025
She is so thoughtful and caring and sets your mind at ease
- 5 out of 5 starsReviewed on 6/4/2025
Samantha is the BEST. She's so caring and knowledgeable. I'm always comfortable talking about anything with her. I very highly recommend her
- 5 out of 5 starsReviewed on 3/25/2025
She went above and beyond was very thorough and supportive. One of the best appointments I have had in managing my care.
- 5 out of 5 starsReviewed on 3/22/2025
Very thorough. First time meeting with her.